Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375742 | 0.81 | MET (0.52) | AHRALDH1A1KMT2ACNR1MET | |
| Hydrochloric Acid SCHEMBL1373870 | 0.80 | MET (0.51) | AHRALDH1A1KMT2ACNR1MET | |
| SCHEMBL3516336 | 0.77 | AHR (0.44) | KDM4EMAPTAHRALDH1A1NPSR1 | |
| SCHEMBL27631474 | 0.76 | LMNA (0.44) | KDM4EMAPTAHRALDH1A1NPSR1 | |
| SCHEMBL1372639 | 0.76 | AHR (0.62) | KDM4EMAPTAHRALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL1373594 | 0.75 | AHR (0.60) | KDM4EMAPTAHRALDH1A1NPSR1 | |
| SCHEMBL1374787 | 0.73 | AHR (0.42) | KDM4EMAPTPOLBAHRALDH1A1 | |
| SCHEMBL15603760 | 0.72 | HTR3A (0.56) | KDM4EMAPTPOLBALDH1A1GAA | |
| SCHEMBL4938909 | 0.72 | HTR3A (0.51) | KDM4EMAPTPOLBAKR1C3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1373665 | 0.72 | AHR (0.41) | KDM4EMAPTPOLBAHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104027333-B | Compounds And Compositions For Treatment Of Cancer | 逊尼希思制药公司 | 2017-05-17 | — | — | CN | disclosed |