Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127344 | 0.81 | TSHR (0.38) | LMNATSHRHCAR2SMN1; SMN2 | |
| SCHEMBL9113376 | 0.79 | LMNA (0.46) | LMNATSHRHCAR2MAPTFAAH | |
| SCHEMBL9113382 | 0.79 | LMNA (0.46) | LMNATSHRHCAR2MAPTFAAH | |
| SCHEMBL27844940 | 0.79 | LMNA (0.48) | LMNATSHRHCAR2MAPTFAAH | |
| SCHEMBL7209244 | 0.77 | LMNA (0.50) | LMNATSHRHCAR2MAPTFAAH | |
| SCHEMBL27111981 | 0.76 | LMNA (0.43) | LMNATSHRMAPTFAAHMGLL | |
| SCHEMBL14899320 | 0.76 | LMNA (0.50) | LMNATSHRMAPTFAAHALDH1A1 | |
| SCHEMBL28332773 | 0.76 | LMNA (0.55) | LMNAHCAR2MAPTFAAHALDH1A1 | |
| SCHEMBL28269587 | 0.75 | LMNA (0.42) | LMNATSHRMAPTALDH1A1PGR | |
| SCHEMBL514518 | 0.75 | FAAH (0.49) | LMNATSHRHCAR2MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467464-A | (E) 2 isopropyl 5 methyl 3,5 hexadienoic acid ester compounds and its production method and produce (E) 2 isopropyl 5 methyl 3 using it, 5 hexadienols and the method for (E) 2 isopropyl 5 methyl 3,5 hexadienyl carboxylate | 信越化学工业株式会社 | 2017-03-01 | — | — | CN | disclosed |