Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28952969 | 0.86 | WNT1 (0.40) | WNT1DYRK1AMCHR1CHKADRD4 | |
| SCHEMBL28127735 | 0.76 | DYRK1A (0.49) | WNT1DYRK1ABRD4CREBBP | |
| SCHEMBL28127407 | 0.71 | HRH3 (0.39) | WNT1DYRK1AMCHR1 | |
| SCHEMBL28127729 | 0.70 | NR3C1 (0.39) | WNT1DYRK1AMCHR1ALDH1A1HTT | |
| SCHEMBL28127736 | 0.70 | NR3C1 (0.39) | WNT1DYRK1AMCHR1ALDH1A1HTT | |
| SCHEMBL28127382 | 0.69 | NR3C1 (0.40) | WNT1DYRK1A | |
| SCHEMBL28127399 | 0.69 | LRRK2 (0.51) | — | |
| SCHEMBL28127716 | 0.69 | LRRK2 (0.51) | — | |
| SCHEMBL28839832 | 0.69 | NR3C1 (0.40) | WNT1DYRK1AMCHR1ALDH1A1HTT | |
| SCHEMBL22926449 | 0.68 | BRD4 (0.36) | MCHR1HDAC1HDAC2BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106535890-A | 5-substituted indazole-3-carboxamides and preparation and use thereof | 萨穆梅德有限公司 | 2017-03-22 | — | — | CN | claimed |