Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.40 |
| ▸ | PGR | P06401 | 7/20 | 0.39 |
| ▸ | WNT1 | P04628 | 2/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28127736 | 0.86 | NR3C1 (0.39) | NR3C1PGRWNT1DYRK1AAR | |
| SCHEMBL28127729 | 0.86 | NR3C1 (0.39) | NR3C1PGRWNT1DYRK1AAR | |
| SCHEMBL28127382 | 0.85 | NR3C1 (0.40) | NR3C1PGRWNT1DYRK1AAR | |
| SCHEMBL28127407 | 0.85 | HRH3 (0.39) | NR3C1PGRWNT1DYRK1AMCHR1 | |
| SCHEMBL28127486 | 0.83 | NR3C1 (0.41) | NR3C1PGRWNT1DYRK1AAR | |
| SCHEMBL28839870 | 0.82 | DYRK1A (0.42) | NR3C1WNT1DYRK1A | |
| SCHEMBL28127399 | 0.80 | LRRK2 (0.51) | — | |
| SCHEMBL28127716 | 0.80 | LRRK2 (0.51) | — | |
| SCHEMBL28127712 | 0.70 | DYRK1A (0.43) | NR3C1PGRWNT1DYRK1A | |
| SCHEMBL28127717 | 0.69 | DRD2 (0.51) | NR3C1PGRWNT1DYRK1AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106535890-A | 5-substituted indazole-3-carboxamides and preparation and use thereof | 萨穆梅德有限公司 | 2017-03-22 | — | — | CN | claimed |