Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170527 | 0.87 | CTSB (0.54) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL83798 | 0.84 | GPR35 (0.60) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL1531285 | 0.82 | GPR35 (0.58) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL29423526 | 0.82 | CYP1A2 (0.43) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL22690154 | 0.82 | CYP1A2 (0.43) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL28382771 | 0.81 | CYP1A2 (0.57) | GPR35ALDH1A1TSHRTP53HPGD | |
| SCHEMBL13622923 | 0.80 | MEN1 (0.46) | ALDH1A1TSHRMAPTMEN1KMT2A | |
| SCHEMBL31267416 | 0.80 | POLB (0.43) | ALDH1A1TSHRSMN1; SMN2GAAMAPT | |
| SCHEMBL3596469 | 0.80 | CYP3A4 (0.54) | ALDH1A1TSHRGAATHRBMAPT | |
| SCHEMBL20214378 | 0.80 | ALDH1A1 (0.49) | ALDH1A1TP53MAPK1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349233-B | 3, 4-diphenyl-4H-1, 2, 4-triazole derivative and preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2021-06-01 | — | — | CN | disclosed |
| CN-106349233-A | 3,4-diphenyl-4H-1,2,4-triazole derivative as well as preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2017-01-25 | — | — | CN | disclosed |