Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 12/20 | 0.43 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12804260 | 0.87 | MMP2 (0.49) | CHEK2P2RY14LCKPKN1PKN2 | |
| SCHEMBL24950452 | 0.85 | SMN1; SMN2 (0.55) | CHEK2P2RY14SMN1; SMN2CASP3SENP8 | |
| SCHEMBL30201440 | 0.85 | SMN1; SMN2 (0.55) | CHEK2P2RY14SMN1; SMN2CASP3SENP8 | |
| SCHEMBL30344312 | 0.76 | PLG (0.55) | CHEK2LCKPKN1PKN2PLG | |
| SCHEMBL27279095 | 0.76 | LCK (0.52) | CHEK2LCKPKN1PKN2PLG | |
| SCHEMBL10053488 | 0.75 | CHEK2 (0.49) | CHEK2LCKPKN1PKN2PLG | |
| SCHEMBL2977967 | 0.74 | KDM4E (0.53) | SMN1; SMN2 | |
| SCHEMBL327063 | 0.73 | HSD17B10 (0.56) | CHEK2LCKPLGPLAUCASP3 | |
| Hydrochloric Acid SCHEMBL8915608 | 0.73 | ALDH1A1 (0.68) | LCK | |
| SCHEMBL4435557 | 0.73 | LCK (0.47) | CHEK2LCKPKN1PKN2PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478500-A | Carboxylic acid-substituted（Miscellaneous）Aromatic ring analog derivative and its production and use | 广东东阳光药业有限公司 | 2017-03-08 | — | — | CN | disclosed |