Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24950452 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL28128641 | 0.85 | CHEK2 (0.43) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL3922415 | 0.83 | CASP3 (0.54) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL30445643 | 0.75 | HSD17B10 (0.61) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL31721323 | 0.75 | CASP3 (0.60) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL69851 | 0.75 | HSD17B10 (0.61) | CASP3SENP8SENP7SENP6KDM4E | |
| SCHEMBL24950978 | 0.74 | TAS1R3 (0.52) | KDM4EALDH1A1 | |
| SCHEMBL19476290 | 0.74 | CASP3 (0.58) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL233323 | 0.74 | CASP3 (0.58) | SMN1; SMN2CASP3SENP8SENP7SENP6 | |
| SCHEMBL5868213 | 0.74 | CASP3 (0.58) | SMN1; SMN2CASP3SENP8SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117729914-A | Serotonin 5-HT2B inhibiting compounds | 硕腾服务有限责任公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2023009330-A1 | SEROTONIN 5-HT2B INHIBITORY COMPOUNDS | ZOETIS SERVICES LLC (US) | 2023-02-02 | — | — | WO | disclosed |