Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 16/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 13/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | USP14 | P54578 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995117 | 0.78 | CYP11B2 (0.44) | CYP11B2CYP11B1HRH3 | |
| SCHEMBL20340036 | 0.78 | CYP11B2 (0.44) | CYP11B2CYP11B1HRH3 | |
| SCHEMBL28129146 | 0.76 | XDH (0.44) | CYP11B2 | |
| SCHEMBL20906149 | 0.75 | CYP11B1 (0.37) | CYP11B2CYP11B1USP14 | |
| SCHEMBL20340150 | 0.75 | CYP11B2 (0.71) | CYP11B2CYP11B1 | |
| SCHEMBL30995226 | 0.73 | CYP11B2 (0.53) | CYP11B2CYP11B1 | |
| SCHEMBL30995208 | 0.72 | CYP11B2 (0.40) | CYP11B2CYP11B1 | |
| SCHEMBL30995193 | 0.72 | CYP11B2 (0.40) | CYP11B2CYP11B1 | |
| SCHEMBL27635549 | 0.70 | CYP11B2 (0.43) | CYP11B2CYP11B1KCNH2 | |
| SCHEMBL20340209 | 0.70 | CYP11B2 (0.74) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478500-A | Carboxylic acid-substituted（Miscellaneous）Aromatic ring analog derivative and its production and use | 广东东阳光药业有限公司 | 2017-03-08 | — | — | CN | disclosed |