Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 7/20 | 0.40 |
| ▸ | CDK2 | P24941 | 4/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 2/20 | 0.38 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | BRD1 | O95696 | 4/20 | 0.35 |
| ▸ | BRPF1 | P55201 | 4/20 | 0.35 |
| ▸ | BRPF3 | Q9ULD4 | 3/20 | 0.35 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1113031 | 0.87 | XDH (0.41) | XDHSLC22A12CDC7CYP11B2BRD4 | |
| SCHEMBL10053928 | 0.76 | CDC7 (0.47) | CDC7CDK2MAP3K14TDP2BRD4 | |
| SCHEMBL28128652 | 0.76 | CYP11B2 (0.48) | CYP11B2 | |
| SCHEMBL28264497 | 0.75 | CDC7 (0.42) | CDC7CDK2MAP3K14TDP2CCR9 | |
| SCHEMBL8897533 | 0.75 | PSMB8 (0.38) | CDC7CDK2MAP3K14 | |
| SCHEMBL10022420 | 0.72 | CDC7 (0.40) | CDC7CDK2MAP3K14TDP2CCR9 | |
| SCHEMBL20906154 | 0.72 | XDH (0.50) | XDHSLC22A12KIF11 | |
| SCHEMBL4245796 | 0.72 | ACSS2 (0.47) | CYP11B2 | |
| SCHEMBL8898917 | 0.72 | KMT2A (0.48) | BRD4KIF11BRPF1BRD9 | |
| SCHEMBL19231471 | 0.71 | BRPF1 (0.52) | CDC7CDK2MAP3K14TDP2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106478500-A | Carboxylic acid-substituted（Miscellaneous）Aromatic ring analog derivative and its production and use | 广东东阳光药业有限公司 | 2017-03-08 | — | — | CN | disclosed |