Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 8/20 | 0.55 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | CXCR4 | P61073 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92399 | 0.83 | — | — | |
| SCHEMBL17186490 | 0.74 | PTGIR (0.61) | ADRA2AADRA2BADRA2CLMNAAPOBEC3A | |
| SCHEMBL3169468 | 0.73 | PTGIR (0.60) | ADRA2AADRA2BADRA2CLMNAAPOBEC3A | |
| Hydrochloric Acid SCHEMBL18605409 | 0.73 | PTGIR (0.59) | ADRA2AADRA2BADRA2CLMNAAPOBEC3A | |
| SCHEMBL12603306 | 0.72 | — | — | |
| SCHEMBL17186327 | 0.72 | CXCR4 (0.53) | ADRA2AADRA2BADRA2CLMNAAPOBEC3A | |
| SCHEMBL560405 | 0.72 | LMNA (0.71) | LMNAAPOBEC3AAPOBEC3GGAACTDSP1 | |
| SCHEMBL11132646 | 0.71 | CXCR4 (0.56) | ADRA2AADRA2BADRA2CLMNAAPOBEC3A | |
| SCHEMBL7325195 | 0.71 | NISCH (0.54) | ADRA2AADRA2BADRA2CLMNAAPOBEC3A | |
| SCHEMBL13293408 | 0.71 | ADRA2A (1.00) | ADRA2AADRA2BADRA2CPTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106458868-A | Guanidine compounds and uses thereof | 伊谬诺米特医疗有限公司 | 2017-02-22 | — | — | CN | disclosed |