Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.56 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28128541 | 0.84 | HCRTR1 (0.55) | HCRTR1HCRTR2F10ABL1LMNA | |
| SCHEMBL15264387 | 0.82 | HCRTR1 (0.54) | HCRTR1HCRTR2ABL1LMNA | |
| SCHEMBL25145993 | 0.81 | LMNA (0.54) | CYP1A2CHRM2SLC6A4OPRD1OPRK1 | |
| SCHEMBL17929345 | 0.80 | CXCR4 (0.56) | CHRM2CHRM3 | |
| SCHEMBL18899931 | 0.80 | DDR1 (0.55) | DDR1CYP1A2CHRM2SLC6A4OPRD1 | |
| SCHEMBL15263897 | 0.79 | VEGFA (0.54) | HCRTR1HCRTR2DDR1 | |
| SCHEMBL652911 | 0.77 | HTR3E (0.56) | CYP1A2SLC6A4ABL1LMNANR4A2 | |
| SCHEMBL15264757 | 0.77 | KDM4E (0.59) | HCRTR1HCRTR2LMNA | |
| SCHEMBL10174510 | 0.76 | ABL1 (0.57) | HCRTR1HCRTR2SLC6A4ABL1LMNA | |
| SCHEMBL28129028 | 0.75 | CHRM3 (0.43) | HCRTR1HCRTR2CYP1A2CHRM2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104379578-B | Carbamate compounds and its preparation and application | 阿比德治疗公司 | 2017-06-09 | — | — | CN | disclosed |