SCHEMBL28129137

SCHEMBL28129137

CCC(=O)Cc1cccc(OC)c1OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BCHE P06276 16/20 0.59
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
KDM4E B2RXH2 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
PTGER4 P35408 1/20 0.56
PTGER3 P43115 1/20 0.56
PTGER2 P43116 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6035722 0.88 BCHE (0.63) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL13888119 0.84 BCHE (0.69) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL9802314 0.84 L3MBTL1 (0.69) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL7145344 0.83 HTR1A (0.54) MEN1KMT2AKDM4EL3MBTL1PTGER4
SCHEMBL28123030 0.83 BCHE (0.57) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL6035893 0.80 BCHE (0.68) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL27960171 0.78 NPC1 (0.56) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL28129636 0.78 KDM4E (0.65) BCHEKDM4EL3MBTL1PTGER4PTGER3
SCHEMBL7641375 0.78 NPC1 (0.53) BCHEMEN1KMT2AKDM4EL3MBTL1
SCHEMBL4479762 0.78 KMT2A (0.54) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478394-A A kind of preparation technology of 1 (2 hydroxyl, 3 anisyl) ethyl ketone 贵州大学 2017-03-08 CN disclosed