SCHEMBL6035722

SCHEMBL6035722

COc1cccc(CC(=O)O)c1OCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
BCHE P06276 13/20 0.63
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
L3MBTL1 Q9Y468 2/20 0.60
KDM4E B2RXH2 1/20 0.60
FABP4 P15090 1/20 0.59
FABP5 Q01469 1/20 0.59
PTGER4 P35408 2/20 0.59
PTGER3 P43115 2/20 0.59
PTGER2 P43116 2/20 0.59
PTGER1 P34995 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10591847 0.90 FABP4 (0.72) BCHEMEN1KMT2AL3MBTL1FABP4
SCHEMBL5017858 0.89 FABP4 (0.59) BCHEMEN1KMT2AL3MBTL1FABP4
SCHEMBL28129137 0.88 BCHE (0.59) BCHEMEN1KMT2AL3MBTL1KDM4E
SCHEMBL9802314 0.88 L3MBTL1 (0.69) BCHEMEN1KMT2AL3MBTL1KDM4E
SCHEMBL8733917 0.86 SCN9A (0.53)
SCHEMBL13888119 0.85 BCHE (0.69) BCHEMEN1KMT2AL3MBTL1KDM4E
SCHEMBL6036164 0.84 FABP4 (0.52) MEN1KMT2AKDM4EFABP4FABP5
SCHEMBL6035893 0.84 BCHE (0.68) BCHEMEN1KMT2AL3MBTL1KDM4E
SCHEMBL991380 0.83 KMT2A (0.54) MEN1KMT2AKDM4EFABP4FABP5
SCHEMBL29639215 0.83 KMT2A (0.54) MEN1KMT2AKDM4EFABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060148858-A1 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-07-06 US disclosed
EP-1091958-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2001-04-18 EP disclosed
WO-2000022909-A2 SYSTEMS FOR ORAL DELIVERY BIOTECH AUSTRALIA PTY. LIMITED (AU) 2000-04-27 WO disclosed
WO-2000001692-A1 SALTS OF PAROXETINE SMITHKLINE BEECHAM PLC (GB) 2000-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060148858-A1 1, 2-Azole derivatives with hypoglycemic and hypolipidemic activity GPR119, SLC5A1, CYP4B1 BCHE 1107/4885MEN1 2048/4885KMT2A 1706/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.