Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EYA3 | Q99504 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 8/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | FASN | P49327 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | TPMT | P51580 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1313079 | 0.85 | TPMT (0.56) | TTRTPMTERN1LMNA | |
| SCHEMBL5303103 | 0.84 | TTR (0.52) | EYA3CYP2C19TTRESR1TPMT | |
| SCHEMBL28151234 | 0.84 | CES2 (0.46) | TTRCES2CES1FASNESR1 | |
| SCHEMBL1312438 | 0.79 | KDM4E (0.58) | CYP2C19ESR1TPMTCYP2C9ERN1 | |
| SCHEMBL6723795 | 0.78 | TTR (0.51) | EYA3CYP2C19TTRCES2CES1 | |
| SCHEMBL28104789 | 0.74 | CYP2C9 (0.37) | EYA3CYP2C19TTRESR1TPMT | |
| SCHEMBL6724575 | 0.74 | MAPT (0.56) | EYA3CYP2C19TTRCES2CES1 | |
| SCHEMBL7197434 | 0.72 | AKR1B1 (0.61) | FASNMEN1LMNAKMT2AAKR1B1 | |
| SCHEMBL6732706 | 0.72 | TPMT (0.46) | EYA3CYP2C19TTRESR1TPMT | |
| SCHEMBL6720720 | 0.72 | LMNA (0.62) | EYA3CYP2C19TTRESR1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432229-A | Compounds for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106432229-A | Compounds for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2017-02-22 | — | — | CN | disclosed |