Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GMNN | O75496 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786142 | 0.83 | ALDH1A1 (0.50) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL16326127 | 0.80 | ALDH1A1 (0.61) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL29405270 | 0.79 | ALOX5 (0.55) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL8075421 | 0.79 | GABRA1 (0.64) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL10759830 | 0.77 | CES2 (0.62) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL12856551 | 0.77 | TDP1 (0.57) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL6721207 | 0.76 | GABRA1 (0.59) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL9240475 | 0.76 | TDP1 (0.56) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL2705078 | 0.76 | KDM4E (0.46) | MAPTALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL28215241 | 0.76 | KDM4E (0.46) | MAPTALDH1A1MEN1KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |