Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6103705 | 0.84 | TTR (0.50) | HSD17B10CYP3A4TTRALDH1A1CYP1A2 | |
| SCHEMBL15515932 | 0.77 | IDO1 (0.32) | CYP3A4 | |
| SCHEMBL28129730 | 0.75 | CHEK1 (0.46) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL7643075 | 0.75 | THRB (0.57) | HSD17B10TSHRTTRCYP1A2HPGD | |
| SCHEMBL13185474 | 0.75 | AKR1C2 (0.43) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL7932590 | 0.70 | TTR (0.65) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL422660 | 0.70 | HSD17B10 (0.65) | HSD17B10TSHRCYP3A4TTRRECQL | |
| SCHEMBL7637293 | 0.70 | HSP90AB1 (0.54) | TSHRALDH1A1THRBLMNAMAPT | |
| SCHEMBL5085456 | 0.70 | IDO1 (0.37) | CYP3A4 | |
| SCHEMBL5085475 | 0.70 | IDO1 (0.37) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432229-B | One kind is used for the compound for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-106432229-A | Compounds for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-106432229-B | One kind is used for the compound for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106432229-A | Compounds for treating or preventing hyperuricemia or gout | 江苏新元素医药科技有限公司 | 2017-02-22 | — | — | CN | disclosed |