Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 2/20 | 0.70 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129212 | 1.00 | CHRM3 (0.70) | CHRM3AGTR2LMNAMEN1KMT2A | |
| SCHEMBL18199756 | 0.83 | CHRM3 (1.00) | CHRM3AGTR2LMNAMEN1KMT2A | |
| SCHEMBL5487375 | 0.83 | LMNA (0.72) | CHRM3LMNAMEN1KMT2AUSP2 | |
| SCHEMBL5487379 | 0.83 | LMNA (0.72) | CHRM3LMNAMEN1KMT2AUSP2 | |
| SCHEMBL10953062 | 0.81 | LMNA (0.68) | CHRM3LMNAMEN1KMT2AUSP2 | |
| SCHEMBL10953074 | 0.81 | LMNA (0.68) | CHRM3LMNAMEN1KMT2AUSP2 | |
| SCHEMBL11321330 | 0.80 | LMNA (0.68) | CHRM3LMNAMEN1KMT2AUSP2 | |
| SCHEMBL7365408 | 0.80 | LMNA (0.68) | LMNAMEN1KMT2AUSP2TSHR | |
| SCHEMBL7365405 | 0.80 | LMNA (0.68) | LMNAMEN1KMT2AUSP2TSHR | |
| SCHEMBL20193316 | 0.80 | LMNA (0.64) | CHRM3LMNAMEN1KMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104470903-B | Heterocyclic compounds and methods of their use | 诺华股份有限公司 | 2017-02-22 | — | — | CN | claimed |
| CN-104470903-B | Heterocyclic compounds and methods of their use | 诺华股份有限公司 | 2017-02-22 | — | — | CN | disclosed |