Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 8/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16832843 | 0.93 | PLA2G2A (0.69) | PLA2G2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL15129579 | 0.90 | KDM4E (0.73) | PLA2G2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL16832328 | 0.89 | PLA2G2A (0.64) | PLA2G2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL28130384 | 0.89 | KDM4E (0.68) | PLA2G2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL28131200 | 0.84 | L3MBTL1 (0.50) | PLA2G2AKDM4EALDH1A1HSD17B10L3MBTL1 | |
| SCHEMBL28840836 | 0.83 | L3MBTL1 (0.71) | PLA2G2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL28131095 | 0.83 | PLA2G2A (0.62) | PLA2G2AKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16832599 | 0.81 | PLA2G2A (0.54) | PLA2G2AKDM4EALDH1A1HPGDNR4A2 | |
| SCHEMBL281969 | 0.81 | KDM4E (0.56) | PLA2G2AKDM4EALDH1A1POLBHPGD | |
| SCHEMBL5396165 | 0.81 | KDM4E (0.68) | PLA2G2AKDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106380446-A | Synthesis method of quinoline-2-formic acid ester derivatives | 南阳师范学院 | 2017-02-08 | — | — | CN | disclosed |