Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | PLA2G2A | P14555 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16832843 | 0.93 | PLA2G2A (0.69) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL15129579 | 0.90 | KDM4E (0.73) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL28130383 | 0.89 | PLA2G2A (0.67) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL16832417 | 0.86 | KDM4E (0.72) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL28100584 | 0.85 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL28100426 | 0.84 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL2910558 | 0.84 | PLA2G2A (0.54) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL16832328 | 0.83 | PLA2G2A (0.64) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL24916118 | 0.83 | PLA2G2A (0.53) | KDM4EALDH1A1HPGDHSD17B10POLB | |
| SCHEMBL28602079 | 0.83 | PLA2G2A (0.58) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106380446-B | Synthesis method of quinoline-2 formate derivative | 南阳师范学院 | 2021-06-18 | — | — | CN | disclosed |
| CN-106380446-A | Synthesis method of quinoline-2-formic acid ester derivatives | 南阳师范学院 | 2017-02-08 | — | — | CN | disclosed |