Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131010 | 0.82 | BCL2L1 (0.46) | KDM4EHRH3ALDH1A1CA1CA2 | |
| SCHEMBL2697697 | 0.79 | HTT (0.48) | MAPTNPSR1KDM4ERAB9ALMNA | |
| SCHEMBL28130998 | 0.77 | MAPT (0.44) | MAPTNPSR1KDM4ERAB9ALMNA | |
| SCHEMBL28295037 | 0.72 | MEN1 (0.54) | MAPTNPSR1KDM4EHRH3ALDH1A1 | |
| SCHEMBL1958846 | 0.72 | CA2 (0.42) | MAPTNPSR1KDM4ELMNAHTT | |
| SCHEMBL1699958 | 0.72 | MAPT (0.72) | MAPTNPSR1KDM4ERAB9ALMNA | |
| SCHEMBL30468003 | 0.72 | MAPT (0.72) | MAPTNPSR1KDM4ERAB9ALMNA | |
| SCHEMBL27671287 | 0.71 | ALDH1A1 (0.53) | MAPTNPSR1KDM4ERAB9ALMNA | |
| SCHEMBL16037787 | 0.71 | HTT (0.53) | MAPTNPSR1KDM4ERAB9ALMNA | |
| SCHEMBL1958639 | 0.71 | CA2 (0.41) | MAPTNPSR1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397418-A | APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES | ABBVIE公司 | 2017-02-15 | — | — | CN | disclosed |