Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364170 | 0.91 | LARS1 (0.46) | HTR6LARS1LRRK2CYP3A4CYP2C9 | |
| SCHEMBL2704870 | 0.88 | CYP2C9 (0.49) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL8920560 | 0.86 | CYP2C9 (0.45) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL2703373 | 0.83 | CYP2C9 (0.48) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL8745144 | 0.82 | HDAC1 (0.47) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL4630948 | 0.82 | CYP2C9 (0.47) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL14426918 | 0.79 | NPC1 (0.50) | HTR6CYP3A4CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL1228349 | 0.78 | CYP2C9 (0.58) | HTR6LARS1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29297465 | 0.76 | L3MBTL1 (0.50) | CYP3A4CYP2C9CYP2C19CYP1A2CYP2D6 | |
| SCHEMBL30690007 | 0.76 | ALOX5 (0.53) | LARS1LRRK2KIF11NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113511997-A | Pridopidine analogues, their preparation and use | 普丽莱尼亚神经治疗有限公司 | 2021-10-19 | — | — | CN | claimed |
| CN-113511997-A | Pridopidine analogues, their preparation and use | 普丽莱尼亚神经治疗有限公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-106456618-A | Pridopidine analogues, their preparation and use | 泰华制药工业有限公司 | 2017-02-22 | — | — | CN | disclosed |