Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 4/20 | 0.40 |
| ▸ | EDNRA | P25101 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26581277 | 0.81 | BRD4 (0.50) | KDM4EBRD4ALDH1A1BRPF1SMN1; SMN2 | |
| SCHEMBL28133017 | 0.76 | SCN9A (0.45) | SCN9ASCN5A | |
| SCHEMBL19336961 | 0.74 | L3MBTL1 (0.55) | ALDH1A1 | |
| SCHEMBL2178801 | 0.73 | CA9 (0.45) | BRD4SCN9ASCN5A | |
| SCHEMBL17443787 | 0.72 | BRD4 (0.44) | KDM4EBRD4ALDH1A1BRPF1SMN1; SMN2 | |
| SCHEMBL3283017 | 0.72 | SLC9A1 (0.46) | SMN1; SMN2 | |
| SCHEMBL26581232 | 0.72 | KDM4E (0.50) | KDM4EBRD4ALDH1A1BRPF1SMN1; SMN2 | |
| SCHEMBL31098197 | 0.71 | SMN1; SMN2 (0.45) | KDM4EBRD4ALDH1A1BRPF1SMN1; SMN2 | |
| SCHEMBL2175671 | 0.70 | ALDH1A1 (0.43) | BRD4ALDH1A1SMN1; SMN2SCN9ASCN5A | |
| SCHEMBL2175828 | 0.70 | CREBBP (0.40) | BRD4ALDH1A1SMN1; SMN2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106488916-A | The new 2,5 substituted miazines as PDE inhibitor | 格吕伦塔尔有限公司 | 2017-03-08 | — | — | CN | disclosed |