Styrene — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	2/20	0.45

▸	ALDH1A1	P00352	5/20	0.44

▸	TSHR	P16473	3/20	0.44

▸	SMN1; SMN2	Q16637	2/20	0.39

▸	GLA	P06280	1/20	0.38

▸	MGLL	Q99685	3/20	0.38

▸	MEN1	O00255	2/20	0.38

▸	KMT2A	Q03164	2/20	0.38

▸	TP53	P04637	1/20	0.37

▸	CYP3A4	P08684	1/20	0.37

▸	HIF1A	Q16665	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Styrene SCHEMBL28699410	0.97	TDP1 (0.47)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL1355033	0.90	ALDH1A1 (0.50)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL28133285	0.89	TDP1 (0.49)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL28095487	0.84	ALDH1A1 (0.66)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL29150889	0.83	TDP1 (0.44)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
SCHEMBL10824732	0.81	MGLL (0.53)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL27589205	0.81	TDP1 (0.47)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL28076081	0.81	TDP1 (0.47)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
SCHEMBL1269546	0.80	ALDH1A1 (0.42)	TDP1ALDH1A1TSHRSMN1; SMN2GLA
Styrene SCHEMBL28960149	0.80	TDP1 (0.41)	TDP1ALDH1A1TSHRSMN1; SMN2GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-111094381-B	Process for producing thermoplastic polyoxazolidone polymers	科思创德国股份有限公司	2022-03-22	—	—	CN	disclosed