SCHEMBL28133942

SCHEMBL28133942

N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
REN P00797 1/20 0.60
AGTR2 P50052 1/20 0.57
ITGB2 P05107 2/20 0.57
ICAM1 P05362 2/20 0.57
ITGAL P20701 2/20 0.57
MME P08473 1/20 0.56
ECE1 P42892 1/20 0.56
CYP3A4 P08684 1/20 0.56
SLC7A5 Q01650 1/20 0.56
LTA4H P09960 1/20 0.55
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
NLN Q9BYT8 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29971719 1.00 REN (0.60) RENAGTR2ITGB2ICAM1ITGAL
SCHEMBL27826956 0.95 AGTR2 (0.60) RENAGTR2ITGB2ICAM1ITGAL
SCHEMBL30184773 0.95 AGTR2 (0.60) RENAGTR2ITGB2ICAM1ITGAL
SCHEMBL21828676 0.91 CYP3A4 (0.53) RENITGB2ICAM1ITGALMME
SCHEMBL29971925 0.91 CYP3A4 (0.53) RENITGB2ICAM1ITGALMME
SCHEMBL21828671 0.90 CYP3A4 (0.68) ITGB2ICAM1ITGALCYP3A4SLC7A5
Hydrochloric Acid SCHEMBL20335511 0.90 CYP3A4 (0.52) RENITGB2ICAM1ITGALMME
SCHEMBL13563453 0.89 REN (0.72) REN
Bromide SCHEMBL27422846 0.88 REN (0.58) RENMMEECE1LTA4H
SCHEMBL29380221 0.88 CYP3A4 (0.65) RENITGB2ICAM1ITGALCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117778510-A Preparation method of caper bitter peptide 昆明理工大学 2024-03-29 CN claimed
CN-119874816-A Tartary buckwheat protein source hypolipidemic peptide and application thereof 华南农业大学 2025-04-25 CN disclosed
CN-113248624-B SYNTAC polypeptides and uses thereof 阿尔伯特爱因斯坦医学院 2025-02-07 CN disclosed
CN-113286609-B Multimeric T cell modulating polypeptides and methods of use thereof 库尔生物制药有限公司 2025-01-21 CN disclosed
CN-118895313-A Methods and compositions for genetically modifying and amplifying lymphocytes and modulating their activity 埃克苏马生物技术公司 2024-11-05 CN disclosed
CN-118852456-A Multimeric T cell modulating polypeptides and methods of use thereof CUE生物制药股份有限公司 2024-10-29 CN disclosed
CN-118453840-A Methods for modulating immune responses 库尔生物制药有限公司 2024-08-09 CN disclosed
CN-111479921-B Methods and compositions for genetically modifying and amplifying lymphocytes and modulating their activity 埃克苏马生物技术公司 2024-08-02 CN disclosed
CN-109843929-B Proteolytically cleavable chimeric polypeptides and methods of use thereof 加利福尼亚大学董事会 2024-07-05 CN disclosed
CN-117903282-A T cell modulating multimeric polypeptides and methods of use thereof 库尔生物制药有限公司 2024-04-19 CN disclosed
CN-116057181-A Methods and compositions for modifying and delivering lymphocytes 埃克苏马生物技术公司 2023-05-02 CN disclosed
CN-108884460-B Methods and compositions for modulation of lymphocyte transduction and expansion thereof 埃克苏马生物技术公司 2023-04-28 CN disclosed
CN-115724984-A Autoimmune B cell eliminator molecules and uses thereof 拓创生物科技(苏州)有限公司 2023-03-03 CN disclosed
CN-114164134-B Bifidobacterium longum subspecies longum with functions of preventing and relieving colitis symptoms and application thereof 东北农业大学 2023-03-03 CN disclosed
CN-115702165-A Humanized anti-complement factor Bb antibodies and uses thereof 建新公司 2023-02-14 CN disclosed
CN-115605494-A Multimeric T cell modulating polypeptides and methods of use thereof 株式会社LG化学(KR) 2023-01-13 CN disclosed
CN-108610418-B Anti-complement C1s antibodies and uses thereof 美国比奥维拉迪维股份有限公司 2022-11-01 CN disclosed
CN-115243713-A Methods and compositions for delivering modified lymphocyte aggregates 埃克苏马生物技术公司 2022-10-25 CN disclosed
CN-114164134-A Bifidobacterium longum subspecies longum with functions of preventing and relieving colitis symptoms and application thereof 东北农业大学 2022-03-11 CN disclosed
CN-106573895-A Novel 5-acylsulfanyl-histidine compounds as precursors for the corresponding 5-sulfanylhistidines and disulfides thereof 特瑞海德公司 2017-04-19 CN disclosed