Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28317143 | 0.82 | TDP1 (0.34) | TDP1 | |
| SCHEMBL15884262 | 0.75 | TDP1 (0.40) | TDP1 | |
| SCHEMBL28083974 | 0.74 | — | — | |
| SCHEMBL28074589 | 0.73 | SRC (0.32) | SRC | |
| SCHEMBL28834293 | 0.73 | TDP1 (0.39) | TDP1 | |
| SCHEMBL30951439 | 0.72 | TDP1 (0.38) | TDP1 | |
| SCHEMBL1188816 | 0.71 | TDP1 (0.44) | TDP1 | |
| SCHEMBL29404355 | 0.71 | TDP1 (0.44) | TDP1 | |
| SCHEMBL28115091 | 0.70 | SRC (0.33) | SRC | |
| SCHEMBL30951401 | 0.69 | TDP1 (0.35) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456639-B | Prodrugs of HIV Reverse Transcriptase Inhibitors | 默沙东公司 | 2019-05-10 | — | — | CN | disclosed |
| CN-106456639-A | Prodrugs of hiv reverse transcriptase inhibitors | 默沙东公司 | 2017-02-22 | — | — | CN | disclosed |