Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 9/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27812941 | 0.87 | — | — | |
| Benzene SCHEMBL4297098 | 0.80 | ALDH1A1 (0.43) | LMNATSHRTDP1GLA | |
| SCHEMBL7942 | 0.80 | — | — | |
| Hexane SCHEMBL22686089 | 0.80 | LTA4H (0.43) | TP53CES2CES1 | |
| Butanone SCHEMBL28796800 | 0.79 | ALDH1A1 (0.48) | LMNATSHRTDP1CES2CES1 | |
| Diethylamine SCHEMBL21802591 | 0.78 | HTT (0.42) | LMNATSHRTP53ATML3MBTL1 | |
| SCHEMBL28556422 | 0.78 | TP53 (0.38) | LMNATSHRTP53ATMCES2 | |
| Hydrochloric Acid SCHEMBL4462903 | 0.77 | ALDH1A1 (0.40) | LMNATSHRTDP1GLA | |
| Ammonia Solution, Strong SCHEMBL22686091 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL4462906 | 0.77 | ALDH1A1 (0.40) | LMNATSHRTDP1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106543253-A | Anti-viral nucleoside phosphoramidate and its drug regimen and purposes | 杨学聪 | 2017-03-29 | — | — | CN | disclosed |