Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 2/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.35 |
| ▸ | GLA known ✓ | P06280 | 1/20 | 0.35 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4462903 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRDPP4F2TDP1 | |
| Hydrochloric Acid SCHEMBL28182567 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL5929655 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28188527 | 0.96 | — | — | |
| SCHEMBL7942 | 0.96 | — | — | |
| Benzene SCHEMBL4297098 | 0.96 | ALDH1A1 (0.43) | ALDH1A1TSHRDPP4F2TDP1 | |
| Hydrochloric Acid SCHEMBL28117079 | 0.93 | ALDH1A1 (0.35) | ALDH1A1TSHRDPP4F2TDP1 | |
| Ammonia Solution, Strong SCHEMBL22686091 | 0.92 | — | — | |
| Fluoride SCHEMBL704319 | 0.92 | ALDH1A1 (0.40) | ALDH1A1TSHRDPP4F2TDP1 | |
| SCHEMBL13370283 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3138856-B1 | METHOD FOR PREPARATION OF A CATALYST COMPONENT USED FOR OLEFIN POLYMERIZATION | CHINA PETROLEUM & CHEM CORP (CN) | 2020-11-04 | — | — | EP | claimed |
| US-10174141-B2 | Preparation method of a catalyst component for olefin polymerization | China Petroleum & Chemical Corporation Beijing Research Institute of Chemical Industry, China Petroleum & Chemical Corporation (CN) | 2019-01-08 | — | — | US | claimed |
| EP-3138856-A1 | METHOD FOR PREPARATION OF A CATALYST COMPONENT USED FOR OLEFIN POLYMERIZATION | China Petroleum & Chemical Corporation (CN) | 2017-03-08 | — | — | EP | claimed |
| US-20170051086-A1 | Preparation Method of a Catalyst Component for Olefin Polymerization | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2017-02-23 | — | — | US | claimed |
| CN-115368395-A | Preparation method and application of alkyl aluminoxane | 北京化工大学 | 2022-11-22 | — | — | CN | disclosed |
| CN-109689734-B | Method for continuously producing low alkoxy branched siloxane | 瓦克化学股份公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-106543316-B | Catalyst component for olefin polymerization, catalyst and preparation method thereof | 中国石油化工股份有限公司 | 2021-09-21 | — | — | CN | disclosed |
| EP-3138856-B1 | METHOD FOR PREPARATION OF A CATALYST COMPONENT USED FOR OLEFIN POLYMERIZATION | CHINA PETROLEUM & CHEM CORP (CN) | 2020-11-04 | — | — | EP | disclosed |
| CN-109689734-A | The method of continuous production low-alkoxy branch siloxanes | 瓦克化学股份公司 | 2019-04-26 | — | — | CN | disclosed |
| US-10174141-B2 | Preparation method of a catalyst component for olefin polymerization | China Petroleum & Chemical Corporation Beijing Research Institute of Chemical Industry, China Petroleum & Chemical Corporation (CN) | 2019-01-08 | — | — | US | disclosed |
| EP-3138856-A1 | METHOD FOR PREPARATION OF A CATALYST COMPONENT USED FOR OLEFIN POLYMERIZATION | China Petroleum & Chemical Corporation (CN) | 2017-03-08 | — | — | EP | disclosed |
| US-20170051086-A1 | Preparation Method of a Catalyst Component for Olefin Polymerization | CHINA PETROLEUM & CHEMICAL CORPORATION (CN) | 2017-02-23 | — | — | US | disclosed |
| EP-0287666-A1 | PROCESS FOR POLYMERIZING OLEFINS | Mitsui Chemicals, Inc. (JP) | 1988-10-26 | — | — | EP | disclosed |
| EP-0279863-A1 | CATALYST FOR POLYMERIZING ALPHA-OLEFIN AND POLYMERIZATION PROCESS | MITSUI CHEMICALS, INC. (JP) | 1988-08-31 | — | — | EP | disclosed |
| US-4551439-A | Solid catalyst component for olefin polymerization and process for producing same | CHISSO CORPORATION (JP) | 1985-11-05 | — | — | US | disclosed |
| EP-0049436-B1 | PROCESS FOR PRODUCING HIGHLY STEREOREGULAR ALPHA-OLEFIN POLYMERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-07-24 | — | — | EP | disclosed |
| US-4485035-A | HALOGEN-SILICON, -ALUMINUM, -MAGNESIUM AND -TITANIUM COMPONENTS WITH MONOCARBOXY ESTER AND AN AROMATIC COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-11-27 | — | — | US | disclosed |
| US-4412049-A | Process for producing highly stereoregular α-olefin polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-10-25 | — | — | US | disclosed |
| EP-0079389-A1 | PROCESS FOR PRODUCING PROPYLENE POLYMER OR COPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-25 | — | — | EP | disclosed |
| EP-0049436-A1 | Process for producing highly stereoregular alpha-olefin polymers | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-14 | — | — | EP | disclosed |