Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 17/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27987421 | 0.81 | PRKCI (0.42) | PRKCI | |
| SCHEMBL14955767 | 0.81 | SYK (0.44) | PRKCICDK2 | |
| SCHEMBL14955769 | 0.81 | SYK (0.44) | PRKCICDK2 | |
| SCHEMBL28814769 | 0.74 | PRKCI (0.47) | PRKCIPRKCZ | |
| SCHEMBL28814767 | 0.74 | PRKCI (0.47) | PRKCIPRKCZ | |
| SCHEMBL27987771 | 0.74 | PRKCI (0.47) | PRKCIPRKCZ | |
| SCHEMBL28135187 | 0.69 | CCNT1 (0.46) | PRKCICCNT1CCNKCCNE1CDK2 | |
| SCHEMBL28135186 | 0.69 | CCNT1 (0.46) | PRKCICCNT1CCNKCCNE1CDK2 | |
| SCHEMBL27987404 | 0.69 | AXL (0.43) | — | |
| SCHEMBL27987403 | 0.69 | AXL (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066431-B | Pyrazine kinase inhibitors | 波托拉医药品公司 | 2017-03-08 | — | — | CN | disclosed |