Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19649521 | 0.81 | DRD1 (0.50) | DRD2DRD1DRD5DRD3CA1 | |
| SCHEMBL22681979 | 0.75 | KCNH2 (0.44) | PRMT5WDR77HSP90AA1HSP90AB1DRD2 | |
| SCHEMBL10046126 | 0.75 | DRD2 (0.47) | PIK3CDDRD2DRD1DRD5DRD3 | |
| SCHEMBL28136933 | 0.74 | PTPRC (0.46) | CD274TNKS2PDK2 | |
| SCHEMBL7777278 | 0.73 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1BACE1CA1CA2 | |
| SCHEMBL19175041 | 0.70 | SUV39H2 (0.41) | PIK3CDHSP90AA1HSP90AB1KDM1A | |
| SCHEMBL18949633 | 0.69 | PTGS2 (0.49) | TDP2HSP90AA1HSP90AB1CA1CA2 | |
| SCHEMBL19785375 | 0.69 | HSP90AA1 (0.56) | HSP90AA1HSP90AB1KDM1ACA1CA2 | |
| SCHEMBL28866454 | 0.69 | CYP1A1 (0.53) | PRMT5WDR77HSP90AA1HSP90AB1GSTP1 | |
| SCHEMBL12093637 | 0.68 | DRD2 (0.47) | DRD2DRD1DRD5DRD3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106660982-A | Histone demethylase inhibitors | 赛尔基因昆蒂赛尔研究公司 | 2017-05-10 | — | — | CN | disclosed |