SCHEMBL28136197

SCHEMBL28136197

O=C(O)NCC([N+](=O)[O-])([N+](=O)[O-])[N+](=O)[O-]

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.31
BLM P54132 1/20 0.31
HBB P68871 1/20 0.31
KMT2A Q03164 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10481087 0.79 TSHR (0.32) LMNA
SCHEMBL10481081 0.79 LMNA (0.30) LMNA
SCHEMBL13395557 0.79 TSHR (0.38) LMNAMEN1KMT2AHIF1A
SCHEMBL10481083 0.79 LMNA (0.30) LMNA
SCHEMBL22722908 0.71 ALDH1A1 (0.37) LMNA
SCHEMBL9656289 0.70 ALDH1A1 (0.32)
SCHEMBL9683543 0.68
SCHEMBL2346017 0.68 CYP2D6 (0.39) CYP2D6CYP2C19
SCHEMBL9654637 0.67 HIF1A (0.40) LMNACYP2D6CYP2C19MEN1BLM
SCHEMBL9657658 0.67 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104592057-B Synthesis method of trinitroethyl carbamate 中国科学院上海有机化学研究所 2017-05-10 CN claimed