⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25233113 | 0.86 | HIF1A (0.44) | — | |
| SCHEMBL10901351 | 0.78 | — | — | |
| SCHEMBL9298861 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL8980430 | 0.72 | — | — | |
| SCHEMBL4047411 | 0.71 | CYP2D6 (0.45) | — | |
| SCHEMBL4938940 | 0.70 | — | — | |
| SCHEMBL18420350 | 0.70 | TDP1 (0.53) | — | |
| SCHEMBL8846809 | 0.70 | MEN1 (0.46) | — | |
| SCHEMBL28136197 | 0.68 | LMNA (0.31) | — | |
| SCHEMBL31613206 | 0.68 | CYP2D6 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4341252-A1 | OXOINDOLINE COMPOUND FOR THE TREATMENT OF INFLAMMATORY DISEASES OR CANCER | F. Hoffmann-La Roche AG (CH) | 2024-03-27 | — | — | EP | disclosed |
| EP-0509795-A2 | Carbamates of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-21 | — | — | EP | disclosed |
| US-5118678-A | Antibody inhibitors, antiinflammatory agents, fungicides, antitumor agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |