Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.39 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4359628 | 0.91 | TSHR (0.53) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL28873867 | 0.89 | MEN1 (0.55) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| SCHEMBL1674935 | 0.89 | TSHR (0.56) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| SCHEMBL7650164 | 0.86 | MEN1 (0.58) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Water SCHEMBL5790238 | 0.86 | TSHR (0.53) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Bromide SCHEMBL27927822 | 0.86 | TSHR (0.53) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Water SCHEMBL6891802 | 0.84 | MEN1 (0.55) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Triethylene Glycol SCHEMBL28637373 | 0.79 | CYP3A4 (0.65) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL28256084 | 0.78 | MEN1 (0.48) | CYP3A4SLC5A7TSHRMAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL9403409 | 0.78 | CHRM5 (0.48) | CYP3A4SLC5A7TSHRMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106591897-B | A kind of no cryanide ion liquid copper plating solution and copper-plating technique | 浙江大学 | 2019-05-03 | — | — | CN | disclosed |
| CN-106591897-A | Cyanide-free ionic-liquid copper-plating solution and copper plating process | 浙江大学 | 2017-04-26 | — | — | CN | disclosed |