Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 4/20 | 0.44 |
| ▸ | CHRM3 known ✓ | P20309 | 4/20 | 0.44 |
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28873867 | 0.97 | MEN1 (0.55) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| SCHEMBL1674935 | 0.97 | TSHR (0.56) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| SCHEMBL7650164 | 0.95 | MEN1 (0.58) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Bromide SCHEMBL27927822 | 0.95 | TSHR (0.53) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Water SCHEMBL5790238 | 0.95 | TSHR (0.53) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Water SCHEMBL6891802 | 0.92 | MEN1 (0.55) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Hydrochloric Acid SCHEMBL28136235 | 0.91 | CYP3A4 (0.44) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Triethylene Glycol SCHEMBL28637373 | 0.87 | CYP3A4 (0.65) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Hydrochloric Acid SCHEMBL28256084 | 0.86 | MEN1 (0.48) | TSHRMAPK1CYP3A4SLC5A7MEN1 | |
| Hydrochloric Acid SCHEMBL9403409 | 0.86 | CHRM5 (0.48) | TSHRMAPK1CYP3A4SLC5A7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118197817-A | CNTs-MXenes composite material and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2024-06-14 | — | — | CN | claimed |
| CN-115672278-B | Mecalcidone adsorbent and application thereof | 西南政法大学 | 2024-05-24 | — | — | CN | claimed |
| CN-117926380-A | Recycling method of nickel-cobalt-containing choline chloride-ethylene glycol eutectic solvent electrolysis waste liquid | 昆明理工大学 | 2024-04-26 | — | — | CN | claimed |
| CN-117797820-A | Magnetic composite photocatalyst for removing dye and preparation method and application thereof | 沈阳理工大学 | 2024-04-02 | — | — | CN | claimed |
| CN-117566978-B | Sludge heavy metal recycling extraction method and system | 惠州金茂源环保科技有限公司 | 2024-03-29 | — | — | CN | claimed |
| CN-117737449-A | Method for preparing metallic zinc by selectively leaching zinc calcine of zinc sulfide concentrate by using eutectic solvent | 东北大学 | 2024-03-22 | — | — | CN | claimed |
| CN-117737802-A | Bright ruthenium plating electroplating solution, preparation method and application | 东北大学 | 2024-03-22 | — | — | CN | claimed |
| CN-114164244-B | Method for preparing hesperetin-7-O-glucoside and hesperetin | 华南理工大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117625969-A | Method for extracting and recovering cobalt-containing choline chloride-ethylene glycol eutectic solvent electrolysis waste liquid | 昆明理工大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117566978-A | Sludge heavy metal recycling extraction method and system | 惠州金茂源环保科技有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-106749805-A | A kind of atom transfer radical polymerization method of utilization low temperature eutectic effect | 华中科技大学 | 2017-05-31 | — | — | CN | claimed |
| CN-106676583-A | Method for electrolytically separating stannum-lead alloy through low eutectic solvent | 昆明理工大学 | 2017-05-17 | — | — | CN | claimed |
| CN-106398699-A | Preparation method of composite eluent for removing soil heavy mental | 云南民族大学 | 2017-02-15 | — | — | CN | claimed |
| CN-106011806-A | Method for carrying out chemical nickel-plating on surfaces of ZTA ceramics in ionic liquid | 昆明理工大学 | 2016-10-12 | — | — | CN | claimed |
| CN-106011805-A | Method for carrying out chemical nickel plating on surface of Al2O3 ceramic in ionic liquid | 昆明理工大学 | 2016-10-12 | — | — | CN | claimed |
| CN-105861571-A | Method for catalyzing asymmetric hydrolysis of 1,2-epoxyoctane by soybean epoxide hydrolase | 华南理工大学 | 2016-08-17 | — | — | CN | claimed |
| CN-105720253-A | Carbon-coated lithium manganese phosphate cathode material and preparation method thereof | 广西大学 | 2016-06-29 | — | — | CN | claimed |
| CN-105586580-A | Method for medium-low temperature quick chemical plating of Ni-P based on copper leaching and plating pretreatment | LANZHOU INST CHEMICAL PHYSICS CAS | 2016-05-18 | — | — | CN | claimed |
| CN-102769133-A | Method for synthesizing lithium iron phosphate with hierarchical structure | UNIV FUZHOU | 2012-11-07 | — | — | CN | claimed |
| US-20090288956-A1 | System For Recycling Printed Circuit Boards | ECOSIGHT, LLC | 2009-11-26 | — | — | US | claimed |