Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28873867 | 0.97 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1LMNA | |
| Water SCHEMBL6891802 | 0.97 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL1674935 | 0.97 | TSHR (0.56) | MEN1KMT2ATSHRMAPK1LMNA | |
| Bromide SCHEMBL27927822 | 0.95 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1LMNA | |
| Water SCHEMBL5790238 | 0.95 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL4359628 | 0.95 | TSHR (0.53) | MEN1KMT2ATSHRMAPK1LMNA | |
| SCHEMBL10015967 | 0.88 | MEN1 (0.50) | MEN1KMT2ATSHRMAPK1LMNA | |
| Triethylene Glycol SCHEMBL28637373 | 0.87 | CYP3A4 (0.65) | MEN1KMT2ATSHRMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL28136235 | 0.86 | CYP3A4 (0.44) | MEN1KMT2ATSHRMAPK1LMNA | |
| Hydrochloric Acid SCHEMBL28256084 | 0.86 | MEN1 (0.48) | MEN1KMT2ATSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002536440-A | — | — | 2002-10-29 | — | — | JP | claimed |
| EP-1155007-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. Searle LLC (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000047568-A2 | 1,2-BENZOTHIAZEPINES FOR THE TREATMENT OF HYPERLIPIDEMIC DISEASES | G.D. SEARLE LLC (US) | 2000-08-17 | — | — | WO | claimed |
| EP-2804477-B1 | PROCESS FOR PREPARING CHOLINE HYDROXIDE FROM TRIMETHYLAMINE AND ETHYLENE OXIDE | DOW AGROSCIENCES LLC (US) | 2018-06-27 | — | — | EP | disclosed |
| US-9353045-B2 | Process for preparing choline hydroxide from trimethylamine and ethylene oxide | DOW AGROSCIENCES LLC (US) | 2016-05-31 | — | — | US | disclosed |
| WO-2013109705-A1 | PROCESS FOR PREPARING CHOLINE HYDROXIDE FROM TRIMETHYLAMINE AND ETHYLENE OXIDE | DOW AGROSCIENCES LLC (US) | 2013-07-25 | — | — | WO | disclosed |
| US-20130190534-A1 | PROCESS FOR PREPARING CHOLINE HYDROXIDE FROM TRIMETHYLAMINE AND ETHYLENE OXIDE | DOW AGROSCIENCES LLC (US) | 2013-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190534-A1 | PROCESS FOR PREPARING CHOLINE HYDROXIDE FROM TRIMETHYLAMINE AND ETHYLENE OXIDE | CEPT1, BCHE, CHKB | MEN1 542/4885KMT2A 453/4885TSHR 3006/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.