SCHEMBL28136272

SCHEMBL28136272

C=CCOC(=O)C(C)=COC(=O)C=C

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.36
HPGD P15428 1/20 0.35
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 5/20 0.34
TP53 P04637 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP3A4 P08684 3/20 0.34
HSD17B10 Q99714 1/20 0.34
PTP4A3 O75365 2/20 0.33
PTP4A1 Q93096 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PTP4A2 Q12974 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4805596 0.84 NPSR1 (0.41) TSHRHPGDMAPTALDH1A1TP53
SCHEMBL11576487 0.82 MAPT (0.39) TSHRHPGDMAPTCACNA1BAPBA1
SCHEMBL9248652 0.81 TSHR (0.46) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL8014309 0.79 TSHR (0.38) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL25220076 0.79 TSHR (0.59) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1318983 0.79 TSHR (0.46) TSHRHPGDMAPTALDH1A1TP53
SCHEMBL7117650 0.79 TSHR (0.37) TSHRMAPTCACNA1BAPBA1ALDH1A1
SCHEMBL28304360 0.78 ALDH1A1 (0.36) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL23674606 0.78 TSHR (0.61) TSHRHPGDMAPTALDH1A1TP53
SCHEMBL28113855 0.78 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110734666-B Process for preparing aqueous dispersions of multistage polymer particles 罗门哈斯公司 2023-03-24 CN disclosed
CN-104744912-B Thermoplastic resin composition 奇美实业股份有限公司 2017-04-12 CN disclosed