Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.47 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2817666 | 0.84 | GSK3B (0.48) | SMN1; SMN2KDM4ERAB9AGAAMEN1 | |
| SCHEMBL2815569 | 0.79 | HDAC3 (0.46) | KDM4EALDH1A1HSD17B10DRD2HTR2A | |
| SCHEMBL2818030 | 0.78 | NTRK1 (0.52) | SMN1; SMN2KDM4ERAB9AGAACSNK2A1 | |
| SCHEMBL14314019 | 0.77 | KDM4E (0.65) | SMN1; SMN2KDM4ERAB9AGAAMEN1 | |
| SCHEMBL20181950 | 0.76 | KDM4E (0.64) | SMN1; SMN2KDM4ERAB9AGAAMEN1 | |
| SCHEMBL30068590 | 0.75 | KDM4E (0.62) | SMN1; SMN2KDM4ERAB9AGAAMEN1 | |
| SCHEMBL2817651 | 0.73 | NR1H4 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2814896 | 0.71 | HDAC3 (0.46) | KDM4EGAAALDH1A1HSD17B10DRD2 | |
| SCHEMBL950894 | 0.69 | NPC1 (0.68) | SMN1; SMN2KDM4ERAB9AGAAMEN1 | |
| SCHEMBL38655498 | 0.69 | YTHDC1 (0.71) | SMN1; SMN2KDM4ERAB9AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | ADDEX PHARMA SA (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249123-A1 | NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE | FSHR, GNRHR, SHBG | SMN1; SMN2 4686/4885KDM4E 1395/4885RAB9A 1404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.