Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL22721325 | 0.98 | NFE2L2 (0.58) | NFE2L2TRPA1HTTSRCCYP1A1 | |
| SCHEMBL1654497 | 0.87 | NFE2L2 (0.70) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| SCHEMBL1654495 | 0.87 | NFE2L2 (0.70) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| Phosphoric Acid SCHEMBL30015588 | 0.85 | NFE2L2 (0.47) | NFE2L2TRPA1HTTSRCCYP1A1 | |
| Water SCHEMBL28632016 | 0.85 | NFE2L2 (0.68) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| Sulfuric Acid SCHEMBL563788 | 0.84 | NFE2L2 (0.58) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| Sulfuric Acid SCHEMBL4629396 | 0.84 | NFE2L2 (0.58) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| Ethylene SCHEMBL3620083 | 0.83 | NFE2L2 (0.66) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| Ethylene SCHEMBL3620087 | 0.83 | NFE2L2 (0.66) | NFE2L2TRPA1HTTCYP1A1CYP1A2 | |
| Sulfuric Acid SCHEMBL28329173 | 0.83 | NFE2L2 (0.56) | NFE2L2TRPA1HTTCYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104411171-B | Herbicidal composition having improved herbicidal activity | 石原产业株式会社 | 2017-05-10 | — | — | CN | disclosed |