Propachlor

Propachlor

SCHEMBL2813734

CC(C)N(C(=O)CCl)c1ccccc1.CC(C)c1nn(C(=O)NC(C)(C)C)c(=O)n1N

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 13/20 0.51
LMNA P02545 4/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
TP53 P04637 1/20 0.51
NPSR1 Q6W5P4 2/20 0.32
KMT2A Q03164 7/20 0.32
MEN1 O00255 4/20 0.32
ATM Q13315 1/20 0.32
HTT P42858 3/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 1/20 0.32
MITF O75030 1/20 0.31
PAX8 Q06710 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808731 0.79 TP53 (0.39) ALDH1A1TP53KMT2AMEN1TDP1
Dimethachlor SCHEMBL2814025 0.76 TP53 (0.33) ALDH1A1SMN1; SMN2TP53KMT2AMEN1
Metazachlor SCHEMBL2816390 0.74 NLRP3 (0.32) ALDH1A1TP53POLBTDP1
Pretilachlor SCHEMBL2815535 0.74 NR1I2 (0.56) ALDH1A1TP53KMT2AMEN1TDP1
SCHEMBL2814893 0.73 TP53 (0.46) ALDH1A1SMN1; SMN2TP53KMT2AMEN1
Clopyralid SCHEMBL19463612 0.73 MEN1 (0.33) ALDH1A1KMT2AMEN1L3MBTL1
SCHEMBL2812407 0.72 TDP1 (0.42) ALDH1A1TP53KMT2AMEN1TDP1
Propachlor SCHEMBL65571 0.71 ALDH1A1 (1.00) ALDH1A1LMNASMN1; SMN2TP53NPSR1
Propachlor SCHEMBL1701162 0.71 ALDH1A1 (1.00) ALDH1A1LMNASMN1; SMN2TP53NPSR1
SCHEMBL2812068 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917994-B2 Carbamoyl triazolinone based herbicide combinations and method of use ARYSTA LIFESCIENCE CORPORATION (JP) 2024-03-05 US disclosed
US-11432549-B2 Carbamoyl triazolinone based herbicide combinations and method of use ARYSTA LIFESCIENCE CORPORATION (JP) 2022-09-06 US disclosed
US-20200107547-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use ARYSTA LIFESCIENCE CORP (JP) 2020-04-09 US disclosed
US-20190223439-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use ARYSTA LIFESCIENCE CORPORATION (JP) 2019-07-25 US disclosed
US-10299479-B2 Carbamoyl triazolinone based herbicide combinations and methods of use ARYSTA LIFESCIENCE CORPORATION (JP) 2019-05-28 US disclosed
CN-103907625-A Herbicidal compositions based on carbamoyltriazolinone and methods of use ARYSTA LIFESCIENCE CORP 2014-07-09 CN disclosed
US-20140051579-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2014-02-20 US disclosed
US-20100311589-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE ARYSTA LIFESCIENCE CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917994-B2 Carbamoyl triazolinone based herbicide combinations and method of use DDT, NOTUM, WEE1 ALDH1A1 1478/4885LMNA 4701/4885SMN1; SMN2 4753/4885
US-20190223439-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use DDT, NOTUM, WEE1 ALDH1A1 1478/4885LMNA 4701/4885SMN1; SMN2 4753/4885
US-20200107547-A1 Carbamoyl Triazolinone Based Herbicide Combinations and Method of Use DDT, NOTUM, WEE1 ALDH1A1 1478/4885LMNA 4701/4885SMN1; SMN2 4753/4885
US-20140051579-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHODS OF USE DDT, NOTUM, WEE1 ALDH1A1 1367/4885LMNA 4634/4885SMN1; SMN2 4709/4885
US-11432549-B2 Carbamoyl triazolinone based herbicide combinations and method of use DDT, NOTUM, WEE1 ALDH1A1 1478/4885LMNA 4701/4885SMN1; SMN2 4753/4885
US-20100311589-A1 CARBAMOYL TRIAZOLINONE BASED HERBICIDE COMBINATIONS AND METHOD OF USE DDT, NOTUM, WEE1 ALDH1A1 1478/4885LMNA 4701/4885SMN1; SMN2 4753/4885
US-10299479-B2 Carbamoyl triazolinone based herbicide combinations and methods of use DDT, NOTUM, WEE1 ALDH1A1 1367/4885LMNA 4634/4885SMN1; SMN2 4709/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.