Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 1/20 | 0.35 |
| ▸ | PAM | P19021 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28407338 | 0.94 | TSHR (0.51) | TSHRDGKACES1CES2LMNA | |
| SCHEMBL28173939 | 0.93 | TSHR (0.54) | TSHRDGKACES1CES2LMNA | |
| SCHEMBL28403872 | 0.93 | TSHR (0.54) | TSHRDGKACES1CES2LMNA | |
| SCHEMBL28398377 | 0.93 | TSHR (0.54) | TSHRDGKACES1CES2LMNA | |
| SCHEMBL27685839 | 0.91 | TSHR (0.53) | TSHRDGKACES1CES2LMNA | |
| Hexanoate SCHEMBL28828199 | 0.88 | AKR1B1 (0.52) | TSHRLMNAALDH1A1MAPT | |
| SCHEMBL27691616 | 0.88 | ALDH1A1 (0.39) | TSHRDGKALMNAALDH1A1TK1 | |
| SCHEMBL28774913 | 0.86 | LMNA (0.42) | TSHRDGKALMNAALDH1A1TK1 | |
| SCHEMBL28213970 | 0.86 | LMNA (0.42) | TSHRDGKALMNAALDH1A1TK1 | |
| SCHEMBL19746061 | 0.83 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111240156-A | Photosensitive resin composition, method for producing patterned cured film, and patterned cured film | 东京应化工业株式会社 | 2020-06-05 | — | — | CN | disclosed |
| CN-106573133-A | Implants for localized drug delivery and methods of use thereof | 加利福尼亚大学董事会 | 2017-04-19 | — | — | CN | disclosed |