Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | CTSB | P07858 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | BRD4 | O60885 | 1/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.61 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.61 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.61 |
| ▸ | HTR2C | P28335 | 1/20 | 0.61 |
| ▸ | CTH | P32929 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9299649 | 0.89 | MAPT (0.65) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL2961445 | 0.78 | MAPT (0.66) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL29066533 | 0.76 | KMT2A (0.59) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL9545672 | 0.76 | MAPT (0.86) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL28778116 | 0.76 | POLB (0.57) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL8986382 | 0.76 | SLC40A1 (0.65) | MAPTKMT2AMEN1CTSBMETAP2 | |
| Nitroxoline SCHEMBL29363027 | 0.76 | MAPT (1.00) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL2246159 | 0.76 | KMT2A (1.00) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| Nitroxoline SCHEMBL151248 | 0.76 | MAPT (1.00) | MAPTALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL29066531 | 0.76 | MAPT (0.55) | MAPTALDH1A1KMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565604-A | Synthetic method of 5-nitro-8-carboxamidoquinoline compound | 河南师范大学 | 2017-04-19 | — | — | CN | disclosed |
| CN-106565604-A | Synthetic method of 5-nitro-8-carboxamidoquinoline compound | 河南师范大学 | 2017-04-19 | — | — | CN | disclosed |