SCHEMBL9299649

SCHEMBL9299649

CC(=O)Nc1ccc([N+](=O)[O-])c2cccnc12

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 15/20 0.65
ALDH1A1 P00352 8/20 0.65
LMNA P02545 6/20 0.61
KMT2A Q03164 5/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
MEN1 O00255 4/20 0.61
HTT P42858 4/20 0.61
CTSB P07858 3/20 0.61
KDM4E B2RXH2 3/20 0.61
NPC1 O15118 1/20 0.61
BRD4 O60885 1/20 0.61
HSP90AA1 P07900 1/20 0.61
CHRM1 P11229 1/20 0.61
DRD2 P14416 1/20 0.61
ALOX12 P18054 1/20 0.61
ADRA2B P18089 1/20 0.61
ADRA2C P18825 1/20 0.61
CHRM3 P20309 1/20 0.61
HTR2C P28335 1/20 0.61
CTH P32929 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28138024 0.89 MAPT (0.64) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
Nitroxoline SCHEMBL28276134 0.80 MAPT (0.88) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL645403 0.79 RXFP1 (0.58) MAPTALDH1A1KMT2AMEN1HTT
SCHEMBL28419837 0.78 ATM (0.54) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL29862447 0.78 KMT2A (0.64) MAPTALDH1A1KMT2ASMN1; SMN2MEN1
SCHEMBL23360233 0.78 KMT2A (0.64) MAPTALDH1A1KMT2ASMN1; SMN2MEN1
SCHEMBL17597171 0.78 KDM4E (0.57) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL8986411 0.78 ATM (0.52) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL3128062 0.77 MAPT (0.59) MAPTALDH1A1LMNAKMT2ASMN1; SMN2
SCHEMBL28900353 0.77 MAPT (0.59) MAPTALDH1A1LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5286592-A Electrostatographic toner containing cyan pigment EASTMAN KODAK COMPANY (US) 1994-02-15 US disclosed