Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.69 |
| ▸ | NSD2 | O96028 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | CTSB | P07858 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4507212 | 0.88 | MAPT (0.86) | MAPTKMT2ANSD2NPSR1ALDH1A1 | |
| SCHEMBL5394907 | 0.81 | MAPT (0.56) | MAPTKMT2ANSD2NPSR1ALDH1A1 | |
| SCHEMBL9545607 | 0.77 | MAPT (0.58) | MAPTKMT2ANPSR1ALDH1A1LMNA | |
| SCHEMBL28138024 | 0.76 | MAPT (0.64) | MAPTKMT2ANSD2NPSR1ALDH1A1 | |
| SCHEMBL9299649 | 0.76 | MAPT (0.65) | MAPTKMT2ANSD2NPSR1ALDH1A1 | |
| Nitroxoline SCHEMBL16060959 | 0.76 | MAPT (0.77) | MAPTKMT2ANSD2NPSR1ALDH1A1 | |
| SCHEMBL6657973 | 0.76 | LMNA (0.68) | MAPTKMT2AALDH1A1LMNAMEN1 | |
| SCHEMBL17788961 | 0.75 | GSTM2 (0.90) | KMT2AMEN1POLBHTTGSTM2 | |
| SCHEMBL3181213 | 0.74 | MAPT (0.49) | MAPTKMT2ANSD2NPSR1ALDH1A1 | |
| Nitroxoline SCHEMBL16061009 | 0.73 | MAPT (0.81) | MAPTKMT2ANPSR1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020094-A1 | HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR QUINOLINE | ABBOTT LABORATORIES (US) | 1993-10-14 | — | — | WO | disclosed |