Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.41 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316007 | 0.83 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4EGRNSORT1 | |
| 3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid SCHEMBL27453073 | 0.83 | KDM4E (0.43) | ALDH1A1KDM4EGRNSORT1HCAR3 | |
| SCHEMBL28138855 | 0.82 | SMYD3 (0.42) | KDM4EGRNSORT1CTSVCTSL | |
| SCHEMBL28145141 | 0.82 | SMYD3 (0.42) | KDM4EGRNSORT1CTSVCTSL | |
| SCHEMBL28138790 | 0.78 | CNR1 (0.44) | ALDH1A1GAAKDM4ECNR1CNR2 | |
| SCHEMBL28138791 | 0.72 | PRKCA (0.35) | ALDH1A1GAAKDM4ECNR1CNR2 | |
| SCHEMBL27788389 | 0.72 | ALDH1A1 (0.44) | ALDH1A1GAAKDM4EGRNSORT1 | |
| SCHEMBL17288712 | 0.72 | KDM4E (0.46) | KDM4EGRNSORT1CNR1CNR2 | |
| SCHEMBL20503261 | 0.71 | KDM4E (0.45) | KDM4EGRNSORT1CNR1CNR2 | |
| SCHEMBL2214558 | 0.71 | ALDH1A1 (0.54) | ALDH1A1GAAKDM4EGRNSORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106608873-B | Pyrazol acid amide compounds and the preparation method and application thereof | 湖南化工研究院有限公司 | 2019-05-24 | — | — | CN | disclosed |
| CN-106608873-A | Pyrazole amide compound, and preparation method and application thereof | 湖南化工研究院有限公司 | 2017-05-03 | — | — | CN | disclosed |