3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid

3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid

SCHEMBL27453073

CCCCCCl.Cn1nc(Cl)cc1C(=O)O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
GRN P28799 1/20 0.43
SORT1 Q99523 1/20 0.43
HCAR3 P49019 2/20 0.39
PLA2G2A P14555 1/20 0.38
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
PKM P14618 1/20 0.36
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
KDM5A P29375 1/20 0.34
KDM4C Q9H3R0 1/20 0.34
KDM5B Q9UGL1 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PLA2G4B P0C869 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28138855 0.84 SMYD3 (0.42) KDM4EGRNSORT1HCAR3PLA2G2A
SCHEMBL28145141 0.84 SMYD3 (0.42) KDM4EGRNSORT1HCAR3PLA2G2A
3-Chloro-1-Methyl-1H-Pyrazole-5-Carboxylic Acid SCHEMBL1915166 0.84 GRN (0.56) KDM4EGRNSORT1HCAR3CA12
SCHEMBL28138792 0.83 ALDH1A1 (0.43) KDM4EGRNSORT1HCAR3PLA2G2A
SCHEMBL17288712 0.74 KDM4E (0.46) KDM4EGRNSORT1HCAR3CA12
SCHEMBL21990439 0.73 PLA2G2A (0.58) PLA2G2ATSHRTP53ALDH1A1PLA2G4B
SCHEMBL20503261 0.73 KDM4E (0.45) KDM4EGRNSORT1HCAR3
SCHEMBL2934234 0.72 KDM4E (0.47) KDM4EGRNSORT1HCAR3CA12
SCHEMBL28138790 0.71 CNR1 (0.44) KDM4EHCAR3PLA2G2APKMTSHR
SCHEMBL3058674 0.70 KDM4E (0.39) KDM4EGRNSORT1PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1146764-A Pyrazolecarboxylic acid derivative and plant disease control agent NISSAN CHEMICAL IND LTD (JP) 1997-04-02 CN disclosed