Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetamide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetamide SCHEMBL115226 | 0.96 | — | — | |
| Acetamide SCHEMBL17847056 | 0.96 | LMNA (0.67) | — | |
| Urea SCHEMBL11150246 | 0.88 | — | — | |
| Cyclohexane SCHEMBL8573501 | 0.86 | LMNA (0.53) | — | |
| Urea SCHEMBL1064520 | 0.84 | — | — | |
| Acetone SCHEMBL10591904 | 0.84 | ALDH1A1 (0.55) | — | |
| Acetone SCHEMBL8061699 | 0.84 | ALDH1A1 (0.55) | — | |
| Acetamide SCHEMBL5386560 | 0.83 | LMNA (0.89) | — | |
| Acetamide SCHEMBL4347036 | 0.83 | — | — | |
| Acetamide SCHEMBL8035624 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253516-A1 | A COSMETIC COMPOSITION COMPRISING A RETINOID FOR PROVIDING ANTIAGING BENEFITS | UNILEVER IP HOLDINGS B.V. (NL) | 2022-12-08 | — | — | WO | disclosed |
| US-8771718-B2 | Formulated tick and insect repellent compositions | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-07-08 | — | — | US | disclosed |
| CN-103747777-A | Cassia derivatives | LUBRIZOL ADVANCED MAT INC | 2014-04-23 | — | — | CN | disclosed |
| CN-1816325-B | Hydrophilic adhesives for delivery of herbal medicines | 3M INNOVATIVE PROPERTIES CO | 2010-12-15 | — | — | CN | disclosed |
| US-20100248380-A1 | METHOD AND ASSAYS FOR QUANTITATION OF ACETAMIDE IN A COMPOSITION | ARETE THERAPEUTICS, INC. | 2010-09-30 | — | — | US | disclosed |
| WO-2010105193-A1 | METHOD AND ASSAYS FOR QUANTITATION OF ACETAMIDE IN A COMPOSITION | ARETE THERAPEUTICS, INC. (US) | 2010-09-16 | — | — | WO | disclosed |
| EP-2040555-A2 | FORMULATED TICK AND INSECT REPELLENT COMPOSITIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-04-01 | — | — | EP | disclosed |
| WO-2007133683-A2 | FORMULATED TICK AND INSECT REPELLENT COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070264297-A1 | Formulated tick and insect repellent compositions | 1,4Group, Inc. | 2007-11-15 | — | — | US | disclosed |
| CN-1816325-A | Hydrophilic adhesives for delivery of herbal medicines | 3M INNOVATIVE PROPERTIES CO (US) | 2006-08-09 | — | — | CN | disclosed |
| EP-0737060-B1 | CLEAR ANTIPERSPIRANT STICK | COLGATE PALMOLIVE CO (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-1035830-A1 | COSMETIC COMPOSITIONS WITH DIBENZYLIDENE SORBITOL AND FUNCTIONALIZED SILICONES | Colgate-Palmolive Company (US) | 2000-09-20 | — | — | EP | disclosed |
| EP-1032360-A1 | ANTIPERSPIRANT WITH DIBENZYLIDENE SORBITOL | Colgate-Palmolive Company (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999026598-A1 | ANTIPERSPIRANT WITH DIBENZYLIDENE SORBITOL | COLGATE-PALMOLIVE COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
| WO-1999026603-A1 | COSMETIC COMPOSITIONS WITH DIBENZYLIDENE SORBITOL AND FUNCTIONALIZED SILICONES | COLGATE-PALMOLIVE COMPANY (US) | 1999-06-03 | — | — | WO | disclosed |
| US-5895644-A | STABILITY, RIGIDITY | COLGATE-PALMOLIVE COMPANY (US) | 1999-04-20 | — | — | US | disclosed |
| US-5871720-A | DIBENZYLIDENE SORBITOL AND POLYHYDRIC SOLVENT AS GELS FOR STICKS, ESPECIALLY PROPYLENE GLYCOL | COLGATE-PALMOLIVE COMPANY (US) | 1999-02-16 | — | — | US | disclosed |
| US-5490979-A | Clear antiperspirant stick gelled with dibenzylidene sorbitol and containing a guanidine compound as gel stabilizer, and process of making same | THE MENNEN COMPANY (US) | 1996-02-13 | — | — | US | disclosed |
| WO-1993017655-A1 | TOPICAL AROMATIC RELEASING COMPOSITIONS | RICHARDSON VICKS INC. (US) | 1993-09-16 | — | — | WO | disclosed |
| US-4719102-A | ANTIPERSPIRANT | AMERICAN CYANAMID COMPANY (US) | 1988-01-12 | — | — | US | disclosed |