Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31212623 | 1.00 | HIF1A (0.50) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL498294 | 1.00 | HIF1A (0.50) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL6725266 | 0.85 | BLM (0.59) | CYP3A4MEN1ALOX15TSHRKMT2A | |
| SCHEMBL6674277 | 0.85 | BLM (0.59) | CYP3A4MEN1ALOX15TSHRKMT2A | |
| SCHEMBL5031234 | 0.85 | HIF1A (0.50) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL27945054 | 0.85 | HIF1A (0.50) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL8899299 | 0.84 | KMT2A (0.42) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL3955413 | 0.84 | HIF1A (0.46) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL9839841 | 0.83 | HIF1A (0.53) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 | |
| SCHEMBL27305322 | 0.82 | HIF1A (0.49) | HIF1ASMN1; SMN2CYP3A4LMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113811278-B | Concealment of hypomineralized lesions | 墨尔本大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-113412271-A | Hamiltrin derivatives having cysteine residue | 大日本住友制药株式会社 | 2021-09-17 | — | — | CN | disclosed |
| CN-111051329-A | Hamiltrin derivatives and antibody drug complexes thereof | 大日本住友制药株式会社 | 2020-04-21 | — | — | CN | disclosed |
| CN-111032676-A | Antibody drug complex comprising a hemiasterlin derivative | 大日本住友制药株式会社 | 2020-04-17 | — | — | CN | disclosed |
| CN-105873561-B | Stabilized stannous compositions | 墨尔本大学 | 2020-02-21 | — | — | CN | disclosed |
| CN-109152810-A | Methods and compositions for preventing and treating duchenne muscular dystrophy | 康德生物医疗技术公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-104107417-B | Methods For Preventing Or Treating Insulin Resistance | 康奈尔大学 | 2017-04-12 | — | — | CN | disclosed |