SCHEMBL28144164

SCHEMBL28144164

[CH2]c1ccc2coccc1-2

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.36
CSNK2A1 P68400 1/20 0.33
LPL P06858 1/20 0.32
LIPG Q9Y5X9 1/20 0.32
PELI1 Q96FA3 2/20 0.32
ERN1 O75460 1/20 0.32
MEN1 O00255 2/20 0.30
ALDH1A1 P00352 2/20 0.30
CYP1A2 P05177 2/20 0.30
CYP3A4 P08684 2/20 0.30
CYP2D6 P10635 2/20 0.30
CYP2C19 P33261 2/20 0.30
KMT2A Q03164 2/20 0.30
HSD17B10 Q99714 2/20 0.30
CLK4 Q9HAZ1 2/20 0.30
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
ESR1 P03372 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696358 0.71 IMPDH2 (0.38) IMPDH2CSNK2A1LPLLIPGPELI1
SCHEMBL2008440 0.71 HDAC2 (0.37) IMPDH2CSNK2A1LPLLIPGPELI1
SCHEMBL2774676 0.71 CSNK2A1 (0.34) IMPDH2CSNK2A1LPLLIPGMEN1
SCHEMBL2096773 0.69 LPL (0.35) IMPDH2LPLLIPG
SCHEMBL2095979 0.69 CSNK2A1 (0.33) IMPDH2CSNK2A1MEN1ALDH1A1CYP1A2
SCHEMBL3298791 0.68 LPL (0.46) IMPDH2LPLLIPGERN1MEN1
SCHEMBL1772039 0.68 LPL (0.54) IMPDH2CSNK2A1LPLLIPGERN1
SCHEMBL21295883 0.67 CSNK2A1 (0.34) IMPDH2CSNK2A1LPLLIPGESR1
SCHEMBL96128 0.67 ERN1 (0.51) IMPDH2CSNK2A1PELI1ERN1MEN1
SCHEMBL6599383 0.67 IMPDH2 (0.37) IMPDH2CSNK2A1PELI1ERN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106659161-B Amide compound and its harmful arthropod prevent and kill off purposes 住友化学株式会社 2019-08-02 CN disclosed
CN-106572659-B Harmful arthropod agent for preventing and eliminating containing amide compound 住友化学株式会社 2019-05-10 CN disclosed
CN-106659161-A Amide compound and use of same for noxious arthropod control 住友化学株式会社 2017-05-10 CN disclosed
CN-106572659-A Noxious arthropod control agent containing amide compound 住友化学株式会社 2017-04-19 CN disclosed