SCHEMBL7696358

SCHEMBL7696358

Cc1ccc2coccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 2/20 0.38
LPL P06858 1/20 0.36
LIPG Q9Y5X9 1/20 0.36
CSNK2A1 P68400 1/20 0.33
ENPP3 O14638 1/20 0.33
ENPP1 P22413 1/20 0.33
PDE10A Q9Y233 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 2/20 0.32
CYP1A2 P05177 2/20 0.32
CYP3A4 P08684 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP2D6 P10635 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
PELI1 Q96FA3 2/20 0.32
ERN1 O75460 1/20 0.32
HSPB1 P04792 1/20 0.32
MAPK14 Q16539 1/20 0.32
DRD2 P14416 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28051267 0.82 IMPDH2 (0.47) IMPDH2ENPP3ENPP1ALDH1A1MEN1
SCHEMBL8055265 0.81 ESR1 (0.39) IMPDH2LPLLIPGCSNK2A1ENPP3
SCHEMBL14003430 0.79 S1PR4 (0.39) IMPDH2CSNK2A1PDE10AALDH1A1MEN1
SCHEMBL5795534 0.76 ALDH1A1 (0.43) IMPDH2CSNK2A1PDE10AALDH1A1MEN1
SCHEMBL20777196 0.76 CSNK2A1 (0.41) IMPDH2CSNK2A1PDE10ACYP3A4
SCHEMBL10304989 0.76 ABL1 (0.41) IMPDH2CSNK2A1PDE10AALDH1A1CYP1A2
SCHEMBL28513436 0.74 CSNK2A1 (0.40) IMPDH2CSNK2A1ALDH1A1MEN1CYP1A2
SCHEMBL10035040 0.73 PPARG (0.48) ALDH1A1MEN1CYP1A2CYP3A4KMT2A
SCHEMBL28925250 0.73 ALDH1A1 (0.36) IMPDH2LPLLIPGCSNK2A1ALDH1A1
SCHEMBL20036777 0.73 TOP2A (0.38) IMPDH2LPLLIPGCSNK2A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10251396-B2 Amide compound and use of same for noxious arthropod control SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-04-09 US disclosed
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-10-19 US disclosed
EP-3178322-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL Sumitomo Chemical Company Limited (JP) 2017-06-14 EP disclosed
US-6342497-B1 2″-deoxy hygromycin derivatives PFIZER INC 2002-01-29 US disclosed
US-6313100-B1 ANTIBACTERIAL, ANTIPROTOZOA AGENTS PFIZER INC 2001-11-06 US disclosed
EP-1077984-A1 2\"-DEOXY HYGROMYCIN DERIVATIVES Pfizer Products Inc. (US) 2001-02-28 EP disclosed
US-6040449-A USEFUL FOR FORMING FLUORINE CONTAINING 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES, USEFUL AS ANTAGONIST FOR MUSCARINIC M3 RECEPTORS AND LESS SIDE EFFECT BANYU PHARMACEUTICAL CO LTD (JP) 2000-03-21 US disclosed
WO-1999057127-A1 2'-DEOXY HYGROMYCIN DERIVATIVES PFIZER PRODUCTS INC. (US) 1999-11-11 WO disclosed
US-5948792-A POTENT AND SELECTIVE ANTAGONISTS FOR MUSCARINIC M.SUB.3 RECEPTORS WITH LITTLE SIDE EFFECTS. BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-09-07 US disclosed
EP-0930298-A1 FLUORINATED 1,4-DISUBSTITUTED PIPERIDINE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 1999-07-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170295789-A1 AMIDE COMPOUND AND USE OF SAME FOR NOXIOUS ARTHROPOD CONTROL OPRM1, TRPA1, L3MBTL3 IMPDH2 4570/4885LPL 3462/4885LIPG 3721/4885
US-10251396-B2 Amide compound and use of same for noxious arthropod control OPRM1, TRPA1, L3MBTL3 IMPDH2 4570/4885LPL 3462/4885LIPG 3721/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.