SCHEMBL28145266

SCHEMBL28145266

[CH2]CC1=NOC(COCc2ccccc2)C1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
TAAR1 Q96RJ0 1/20 0.42
HRH4 Q9H3N8 4/20 0.41
HRH3 Q9Y5N1 4/20 0.41
DRD1 P21728 1/20 0.39
TSHR P16473 1/20 0.39
PTPN1 P18031 1/20 0.37
CDC25B P30305 1/20 0.37
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
CTSK P43235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28144148 0.86 MEN1 (0.37)
SCHEMBL28145178 0.86 MEN1 (0.40) LMNATAAR1TSHR
SCHEMBL28144168 0.83 MEN1 (0.37) LMNATAAR1HRH4HRH3
SCHEMBL28145344 0.82 L3MBTL1 (0.38) LMNATAAR1HRH4HRH3
SCHEMBL28145165 0.79 TDP1 (0.51) LMNAHRH3DRD1TSHR
SCHEMBL28290953 0.78 LMNA (0.41) LMNATAAR1HRH4HRH3DRD1
SCHEMBL28145201 0.78 SLC6A2 (0.43) TAAR1
SCHEMBL18936088 0.76 LMNA (0.48) LMNATAAR1HRH4HRH3DRD1
SCHEMBL3143177 0.75 LMNA (0.55) LMNATAAR1HRH4HRH3DRD1
SCHEMBL23544405 0.72 LMNA (0.43) LMNATAAR1HRH4HRH3DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572659-A Noxious arthropod control agent containing amide compound 住友化学株式会社 2017-04-19 CN disclosed