Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19029250 | 0.81 | LCK (0.44) | HDAC6MAPTPARP1CHEK2LCK | |
| SCHEMBL9305906 | 0.80 | HDAC6 (0.40) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL13356595 | 0.80 | RAB9A (0.51) | HDAC6MAPTLMNAMAPK1KMT2A | |
| SCHEMBL1096761 | 0.80 | MAPT (0.53) | HDAC6CSNK2A2CSNK2BMAPTALOX15 | |
| SCHEMBL29364254 | 0.80 | MAPT (0.53) | HDAC6CSNK2A2CSNK2BMAPTALOX15 | |
| SCHEMBL2244354 | 0.79 | MAPT (0.64) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL24072580 | 0.76 | MAPT (0.42) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31208317 | 0.76 | ALDH1A1 (0.50) | MAPTCYP1A2KMT2AKDM4ERAB9A | |
| SCHEMBL22382443 | 0.76 | ALDH1A1 (0.50) | MAPTCYP1A2KMT2AKDM4ERAB9A | |
| SCHEMBL21979448 | 0.73 | HDAC6 (0.48) | HDAC6MAPTALOX15CHEK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106588808-A | Preparation method of benzo[d]oxazole derivative | 长沙深橙生物科技有限公司 | 2017-04-26 | — | — | CN | disclosed |